Synthesis of alginate neoglycolipids / by Rongsong Xu.
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"Innate immunity, one of two arms of the immune system, can provide more rapid defense mechanisms than adaptive immunity in human immune defense systems. The innate immune system recognizes invading pathogens by binding a variety of ligands to the family of Toll-like receptors (TLRs) which play important roles in linking innate and adaptive immunities in host immune defense. Direct application of natural TLR ligands in the pharmaceutical industry is evidently limited due to their complicated components and high toxicity, and hence synthetic TLR ligands have emerged as competitive therapeutic agents involved in various diseases including infection, inflammation and cancers.