Now showing items 1-3 of 3
Synthesis of novel Lipid A analogs as potential ligands for toll-like receptor 4
Lipid A, the glycolipid component of Gram-negative bacterial lipopolysaccharide has been shown to engage the Toll-like receptor 4 (TLR4) signalling pathway. While this signalling cascade results in cellular mediators which ...
C-N bond formation employing palladium and nickel precatalysts containing anionic phosphinobenzimidazole ligands
In this investigation, the catalytic utility of anionic, phosphinobenzimidzoles [Li(THF)2][1a] and [Li(THF)4][1b] in effecting the Buchwald-Hartwig amination reaction was examined. Specifically, the coordination chemistry ...