Browsing Electronic Theses and Dissertations from 2009 by Subject "Immune system"
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Novel toll-like receptor 4 ligands: synthesis, biological studies and applications in molecular vaccines
(2015-06-15)Lipid A, a unique disaccharide glycolipid, is the active principle of Gram-negative bacterial lipopolysaccharide in activating the innate immune response via Toll-like receptor 4 (TLR4). Given the important role that ... -
Synthesis of muramyl dipeptide analogues as immunomodulatory agents
(2018)Peptidoglycan occurs naturally in cell wall structures of almost all types of bacteria. Muramyl dipeptide (MDP) is a fragment of peptidoglycan, which consists of N-acetylmuramic acid that is attached to a dipeptide of ...