Browsing by Discipline
Now showing items 41-60 of 297
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The carcinogenic properties of naturally occurring human papillomavirus 16 E6 oncogene variants
(2013-02-03)Human papillomavirus is the causative agent of the 2nd highest occurring cancer in women, cervical cancer, which is the result of expression of the E6 and E7 oncogenes. Here we challenged the dogma that the oncogenic protein ... -
Causes and consequences of population changes in Black Bay Steelhead, Lake Superior
(2019)Understanding species interactions is an important component of fisheries resource management. Like the other Great Lakes, Lake Superior’s fish species composition (and therefore interactions among species) has been changing ... -
Changes in physiology and reproductive success in fathead minnows (Pimephales promelas) exposed to pulp and paper mill effluent / by Jacob D. Ouellet.
(2008)As part of their manufacturing process, pulp and paper mills release effluent into waterways that may affect the fecundity, morphology, and physiology of invertebrates and vertebrates in the receiving ecosystem (Kovacs et ... -
Characterization of an arsenite-oxidizing caballeronia sp. soil bacterium and its mutualistic relationship with trifolium pratense for arsenic remediation
(2021)The proposed application of the mutualistic interaction between a native arsenicoxidizing soil bacteria and Trifolium pratense in Northwestern Ontario mine sites is a novel approach to remediation. This thesis studies the ... -
Characterization of Campylobacter jejuni growing in biofilms under different conditions
(2005)The viability of C. jejuni biofilms growing in different conditions was investigated by conventional plate counts and microscopy after nucleic acid staining. Differences were detected for each condition tested. However, ... -
Characterization of genetic determinants for growth and structure of Listeria monocytogenes biofilms / by Nicholas Choy.
(2007, c200)This thesis investigated wild-type 'Listeria monocytogenes ' EGD and five of its corresponding mutant strains (M1, M4, M7, M11 and M14) for their ability to form biofilms on glass at 22°C and 37°C, with and without shear ... -
Characterization of rainbow trout (Oncorhynchus mykiss) and fathead minnow (Pimephales promelas) cell lines as models to study pulp and paper effluent effects in fish
(2012-11-10)The effects of aquatic toxicants on fish growth and development have been well-documented, in contrast to the changes in gene expression that necessarily precede them. Many of these toxicants are exogenous compounds that ... -
Characterization of sediment, sewage and 0157 E. coli: a comparison of their virulence genes, biofilm forming capacities, antibiotic resistance and level of reactive oxygen species (ROS)
(2018)Even though sediment Escherichia coli is a common source of contamination in freshwater environments, their virulence and physiological characteristics are not well studied. The goal of this study was to compare the virulence ... -
Characterization of the second internal transcribed spacer (ITS-2)rDNA region among the Elaphostrongylinae (Nematoda:Protostrongylidae)
(2002)Four species of elaphostrongyline nematodes are known to infect cervids in North America. One species, Parelaphostrongylus tenuis, can cause neurologic disease (parelaphostrongylosis) in cervid hosts other than white ... -
Chemoreception in invasive rusty crayfish (Orconectes rusticus): learning and adaptation in aquatic ecosystems of Northwestern Ontario
(2012-11-10)Crayfish utilize chemosensory cues, in addition to other sensory inputs, to mediate a variety of fundamental life processes. Exotic species, like the rusty crayfish (Orconectes rusticus), are known to employ a broader ... -
Chloroplast-based in vitro translation systems
(1987)Intact chloroplasts from 8-9 day old pea seedlings were capable of translating mRNA into proteins at high rates. Such metabolically active chloroplasts were lysed and fractionated further in order to develop a ... -
A combined method for establishing keratinocyte cultures from cervical biopsy specimens and creating patent-derived 3-dimensional organotypic raft cultures
(2018)High-risk types of human papillomavirus (HPV) are responsible for nearly all instances of cervical cancer, and a significant proportion of head and neck cancers. Studying HPV in the laboratory requires the cultivation of ... -
Community dynamics resulting from an experimental pulse fishery on the walleye (Stizostedion vitreum vitreum Mitchill) in Henderson Lake
(1988)Henderson Lake is a small 151 ha boreal percid lake approximately 128km northwest of Thunder Bay. A pulse fishery conducted from 1980 to 1982 inclusively, removed 3226 walleye reducing the stock to very low levels (Reid, ... -
Comparing Canonical and Dicer Substrate Small Interfering RNA and Their Effects on the Silencing of Two Common Human Papillomavirus 16 E6 Variants
(2015)High-risk human papillomaviruses (HPVs), such as HPV16, cause nearly all cases of cervical cancer as well as a number of head and neck cancers. Over expression of the E6 oncoprotein helps drive the malignant phenotype, ... -
Comparison of the yellow perch, Perca flavescens Mitchell, populations in Henderson Lake and Savanne Lake, Ontario
(1984)Yellow perch (Perca flavescens) in Henderson Lake exhibit stunted growth and poor condition at all ages. In addition, they have lower fecundity, longer life span, slower maturation rate, and greater survival compared ... -
Core areas of habitat use : the influence of spatial scale of analysis on interpreting summer habitat selection by moose (Alces alces)
(2005)I investigated summer habitat selection patterns within the home ranges of 60 GPS-collared adult female moose (Alces alces) in northwestern Ontario. I developed a model that identified the ‘summer’ period for moose and ... -
Critical decisions: risk allocation in a model arthropod (Folsomia candida)
(2015-06-15)Risk allocation theory predicts that foraging animals moderate predation risk by allocating their foraging effort and space use according to their energetic demands. Undernourished animals have a greater need for energy ... -
The cumulative effects of hypoxia and hyperglycemia on cardiac oxidative stress
(2014-01-22)Hyperglycaemia-induced oxidative stress plays an important role in cardiomyocyte cell death leading to cardiac dysfunction. Autophagy is an intracellular bulk degradation process and can be induced by stressors such as ... -
Cystathionine γ-lyase and hypoxia : implicating hydrogen sulfide in the hypoxic stress response
(2012-11-10)Hydrogen sulfide (H2 S) has emerged as a novel and important gasotransmitter for the cardiovascular system, where it is generated mainly by cystathionine γ-lyase (CSE). Abnormal metabolism and functions of the H2 S/CSE ... -
The Decline of a Northern Lake Superior marsh : a study of the cause and effect
(2009)This study quantified the loss of vegetation in Mission Marsh located within the city limits of Thunder Bay on the northern shore of Lake Superior, suggested the most likely cause of this vegetation loss, and examined in ...