Browsing by Title
Now showing items 770-789 of 3539
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Development of a protocol to profile the gonadal steroid intermediates of vitellogenic ovaries from fathead minnows, pimephales promelas
(1996)This research developed a protocol to extract, isolate, detect, and measure the intermediates involved in ovarian steroid biosynthesis by Pimephales promelas to be used in bleached kraft mill effluent chronic toxicity ... -
Development of a scale to assess individual differences in children's trust-value basis of friendship / Cathy J. Morgan.
(1992)Rotenberg (1986, 1991) has shown that children acquire a "trustvalue" basis of friendship, whereby friendship is a function of how much a child believes a peer will keep secrets, promises and tell the truth. The purpose ... -
Development of a toxicity early warning system (TEW)
(2006)Biomonitoring is a practice that has over time developed into a remarkably accurate form of detecting toxicity in the environment. The Toxicity Early Warning system (TEW) is a Real-Time Biomonitoring system developed to ... -
Development of an 18F radiolabeling method using solid phase chemistry
(2023)New radiotracers are constantly being developed to expand the clinical applications of positron emission tomography (PET). One of the challenges in the development of PET tracers is the incorporation of a positron emitting ... -
Development of an empathic, strong, resilient adolescent: the association of perceived care
(2018)The ability to experience and understand another person’s feelings (empathy), to successfully adapt amidst stress (resilience), and to harness and utilize personal skills (psychological strengths) are dynamic qualities ... -
The development of an in-situ ATR-FTIR technique for the study of nanomaterials
(2009)The Fourier Transform Infrared Spectroscopy technique utilizes a short acquisition time and high sensitivity to function as a strong analytical tool in electrochemical studies. This work will focus on the development of ... -
Development of bacterial systems for the production of cellulase and bioethanol
(2013-02-01)The wide varieties of extant bacterial species are often resistant to various environmental stresses. This demonstrates their frequent ability to adapt to and thrive in challenging environments. One such adaptation in ... -
Development of graphite based nanomaterials for green chemistry applications
(2017)Graphite is a valuable natural resource and useful carbon allotrope that has been explored for various applications. Graphene is a two-dimensional (2D) transparent material, which is the strongest, thinnest, and most ... -
The development of hypothesis testing behaviour in children
(1973)This experiment investigated whether six, eight, and ten year-old children are capable of simultaneously using more than one hypothesis at a time, or whether children can test only one at a time in a discrimination learning ... -
Development of junior intermediate preservice teachers' mathematical knowledge and values / by Carlos Zerpa.
(2008)This research thesis is composed of two studies. The first study examined the validity and reliability of a locally developed instrument called the Perceptions of Mathematics (POM) questionnaire (Kajander, 2005). The POM ... -
Development of key components of a nitrogen budget for a forested watershed on the Canadian boreal plain
(2009)This investigation, which took place as part of the Forest Watershed and Riparian Disturbance (FORWARD) study in west-central Alberta on the Boreal Plain, measured key components of a nitrogen (N) budget in a relatively ... -
Development of modulators targeting G proteincoupled receptors using a combination of conventional drug discovery methodologies and artificial intelligence techniques
(2023)Lysophosphatidic acid receptor 1 (LPA1) is one of six G protein-coupled receptors (GPCRs) in the LPA receptor family (LPA1-6) and is activated by lysophosphatidic acid (LPA). LPA1 is involved in a wide range of cellular ... -
The development of molecular probes for the in vitro and in vivo study of glucocerebrosidase
(2017)Parkinson’s Disease (PD) is one of the most common neurodegenerative diseases in the world. Despite its prevalence, the disease is difficult to diagnose early with the vast majority of individuals already having significant ... -
Development of multi-probe fluorescence-based assay for boNTA detection
(2015-08-05)Botulinum neurotoxins (BoNTs) cause the lethal disease botulism through the inhibition of acetyl choline secretion by the cleavage of crucial SNARE proteins. Determination of critical residues in the protein sequence of ... -
Development of nanostructured material based electrochemical sensors for food safety and quality control
(2019)The issue of foodborne related illnesses due to additives and contaminants poses a significant challenge to food processing industries. Electrochemical-based strategies offer simple and robust analytical tools, which are ... -
Development of nonlinear 3-D, and novel 2-D optical microscope imaging systems for time-lapse imaging
(2004)The design and development of a nonlinear two-photon, 3-D microscope imaging system, software for manipulation of 2-D and 3-D images, and the operation of a novel 2-D imaging system used for monitoring cultured live cell ... -
Development of optimal breeding zones for white spruce in Ontario under current, past, and anticipated future climate change / by Ashley Marie Thomson.
(2008)Tree breeding zones are delimited areas where trees are selected and bred, and their progeny are planted. Within these zones, the level of adaptation between seedlings and planting sites is controlled to ensure adequate ... -
Development of restrictive disclosure in children's communication with peers
(1986)Research supports the conclusion that adults show a pattern of restrictive disclosure in which they choose to disclose intimate information to friends rather than nonfriends. From a developmental perspective, however, ... -
Development of simulation and machine learning solutions for social issues
(2020)When developing solutions for social issues, it can be difficult to evaluate the impact they may have without a real world implementation. This may not be possible for reasons such as resource, time, and monetary ... -
A device for performing sonoporation on adherent cell cultures
(2015-06-15)Sonoporation is a method for inducing a transient increase in the permeability of cell membranes to otherwise impermeable compounds using ultrasound. This technique has therapeutic potential as it allows for localized ...