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Activity of liposomal taxol against breast cancer cells / by Melanie Heney.
(2007)Taxol (paclitaxel) is one of the most effective chemotherapeutic agents used for the treatment of multiple cancers, including breast, ovarian, and, non-small-cell lung cancer. However, development of taxol resistance with ... -
The cumulative effects of hypoxia and hyperglycemia on cardiac oxidative stress
(2014-01-22)Hyperglycaemia-induced oxidative stress plays an important role in cardiomyocyte cell death leading to cardiac dysfunction. Autophagy is an intracellular bulk degradation process and can be induced by stressors such as ... -
The effects of naturally-derived plant compounds on pseudomonas aeruginosa pathogenicity
(2014-12-12)Pseudomonas aeruginosa has risen as one of the most resistant bacterial pathogens affecting people worldwide. Inefficacy of current antimicrobial treatments to relieve P. aeruginosa infections demands the need for novel ... -
Improved anti-melanoma and anti-melanogenic effects of birch bark triterpenes delivered in ethosomes
(2018)North American birch species of the boreal forest contain significant amounts of pentacyclic triterpenes in their outer bark. Betulin (BE) and betulinic acid (BA), pentacyclic triterpenes readily extracted from outer birch ... -
Lipoic acid and its potential role in the treatment of oxidative-induced injury of A549 lung epithelial cells
(2013-02-01)Oxidative stress is the imbalance between prooxidants and antioxidants within a cell that can cause and/or contribute to the progression of many pathological conditions. Reactive oxygen species (ROS) formed from the ... -
The Role of free- and liposomal-N-acetycysteine in paraquat-induced cytotoxicity
(2012-11-10)Paraquat (PQ), one of the most commonly used herbicides worldwide, is hightly toxic to humans and exposure can result in severe clinical situations with no effective treatments available. The toxicity of PQ has been ...
