Retrospective theseshttps://knowledgecommons.lakeheadu.ca/handle/2453/122024-03-29T06:24:23Z2024-03-29T06:24:23ZImmunological consequences of chemically induced generalized motor epilepsyChretien, Rolandhttps://knowledgecommons.lakeheadu.ca/handle/2453/45102019-11-30T03:45:58Z1990-01-01T00:00:00ZImmunological consequences of chemically induced generalized motor epilepsy
Chretien, Roland
The purpose of this study was to determine if the stress created by a generalized motor seizure was significant enough to alter the immune response. Criterion measures of anitgen binding capacity (ABC) to human serum albumin (HSA) were obtained from 39 female and 36 male Satinder's Heterogenous Strain (SHS) albino rats. Within 30 seconds after a second HSA injection (booster), rats were either injected with METRAZOL to produce generalized (motor) convulsions, or with CYCLOPHOSPHAMIDE, an immunosuppressive drug (comparator treatment). A third group served as a saline-injection control and a fourth as an undisturbed control group. Multivariate analysis of variance (Manova) demonstrated a highly significant immunosuppression 4 days later in rats that had displayed brief motor convulsions and had been administered cyclophosphamide. Injection and undisturbed controls did not differ significantly from each other. By the 10th day after the booster and treatments, ABC measures for the drug treated rats (METRAZOL, CYCLOPHOSPHAMIDE) were not significantly different from controls. However on the 10th day females showed significantly higher ABC measures than did males. The degree of immunosuppression seen on day four was moderately correlated to the severity of the seizure observed. These results suggest that the seizuring of an animal is a stressful event capable of suppressing humoral immunity, and that the degree of suppression is positively correlated to the severity of the seizure.
1990-01-01T00:00:00ZReturn to innocenceZoccole, Owenhttps://knowledgecommons.lakeheadu.ca/handle/2453/44572019-11-07T03:45:44Z1997-01-01T00:00:00ZReturn to innocence
Zoccole, Owen
Can native people of today return to live in a "traditional" lifestyle? This was the question that the people of Lac des Milles Lacs through their attempt to return to their homeland, posed in 1988. Five families, responding to imposed restrictions, government regulations and the impact of modern society, moved to recreate their community on the traditional lands of thier people.
1997-01-01T00:00:00ZWater chemistry: its effects on amphibians in Northwestern Ontario, CanadaSanzo, Domenicohttps://knowledgecommons.lakeheadu.ca/handle/2453/44532019-11-05T03:45:41Z2004-01-01T00:00:00ZWater chemistry: its effects on amphibians in Northwestern Ontario, Canada
Sanzo, Domenico
Understanding the role that abiotic environmental factors play in determining the distribution of organisms is of fundamental importance to ecologists. Most amphibians are inherently dependent on aquatic habitats and differences in water may influence community structure. However, few comprehensive studies of amphibian distribution in relation to water chemistry exist, but they suggest that the importance of chemistry may differ among regions. The boreal forest contains nearly half of the world's freshwater wetlands, but its amphibian ecology is poorly understood relative to other biomes. I sampled 73 wetlands in northwestern Ontario for presence/absence of amphibians using repeated day and night visits between April and August 2003.
2004-01-01T00:00:00ZPhysico-chemical properties of soils associated with logged forest and areas converted to teak (Tectana grandis Linn. F)Salifu, Francis K.https://knowledgecommons.lakeheadu.ca/handle/2453/44522019-11-05T03:45:40Z1997-01-01T00:00:00ZPhysico-chemical properties of soils associated with logged forest and areas converted to teak (Tectana grandis Linn. F)
Salifu, Francis K.
This rapid and extensive introduction of teak to satisfy a predicted wood shortage in Ghana has given rise to the question of the short/long-term effects that management of teak plantations might have on soil properties. No research data is currently available to answer this question.
1997-01-01T00:00:00Z