Browsing Electronic Theses and Dissertations by Discipline "Biotechnology"
Now showing items 21-38 of 38
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Hydrogen sulfide modulates gluconeogenesis and mitochondrial biogenesis in mouse primary hepatocytes
(2016)Among many endogenous substances that regulate hepatic energy production is the gasotransmitter hydrogen sulfide (H2S). In the liver, H2S production is largely catalyzed by cystathionine γ-lyase (CSE) and, to a lesser ... -
Improving Novel Gene Discovery in High-Throughput Gene Expression Datasets
(2012-11-10)High-throughput gene expression datasets (including RNA-seq and microarray datasets) can quantify the expression level of tens of thousands of genes in an organism, which allows for the identification of putative functions ... -
Interaction of lignin derivatives with polymers, ions and soft surfaces in aqueous systems
(2021)Lignin is one of the most abundant biopolymers on earth which has recently gained considerable attention due to its unique potentials to be used in many applications. Many efforts have been made in improving the compatibility ... -
Investigation on anti-proliferative effect of gyrophoric acid from the lichen Umbilicaria muhlenbergii on cancer cells
(2021)Natural products, including primary and secondary metabolites, are small molecules produced by any organism. As important sources of drug components, natural products may be isolated to small fractions with different ... -
Kinetic and thermodynamic studies on pyrolysis of waste HDPE polymers
(2017)Pyrolysis is a promising technology for converting waste plastic into high-value hydrocarbons, which can help to protect the environment and improve the waste management industry. Available methods for finding kinetic ... -
Lignin-based flocculant and dispersant for wastewater treatment
(2018)The wastewaters produced from different industries contain fine and charged suspended particles and other impurities. Today, the removal of these colloidal particles from the wastewater has become a serious challenge for ... -
Long term DNA storage evaluation and methodology
(2021)DNA preservation over the long term is a considerable problem for many fields that still lack a viable, cost-effective, long-term solution. The considerable amount of genetic material that is currently aging in facilities ... -
Metal induced olfactory impairment in fish: gene expression, protection and recovery
(2014)To play their ecological role in an ecosystem, a fully functioning olfactory system is vital for fishes. A fish's olfactory system is very sensitive to low concentrations of contaminants. A great deal of research has ... -
Microbial production of value-added products from wood hemicellulose prehydrolysate
(2020)Hemicellulose, the second most abundant polymer in nature, has the great potential to be used for the production of biochemicals under the concept of biorefining. As hemicellulose is watersoluble, it can also be easily ... -
Modelling the molecular mechanisms of biocompatibility of artifical materials
(2015)One of the most common reasons for implant failure is immune rejection. Implant rejection leads to additional surgical intervention and, ultimately, increases health cost as well as recovery time. Within a few hours after ... -
Nanomaterial-based Electrochemical Sensors for the Detection of Glucose and Cholesterol
(2011)Electrochemical detection methods are highly attractive for the monitoring of glucose, cholesterol, cancer, infectious diseases, and biological warfare agents due to their low cost, high sensitivity, functionality despite ... -
Nanomaterials based electrochemical approaches for biosensing and bacterial disinfection
(2017)Electrochemical approaches to myriad medical and environmental challenges are highly attractive due to their strong potential for extensive and green applications. Point of care diagnostics through the electrochemical ... -
New generation of dispersants by grafting lignin or xylan
(2017)Synthetic dispersants are commonly used in the stabilization of various colloidal suspensions. However, their non-biodegradable and toxic natures hamper their industrial use. The use of natural polymers as dispersants for ... -
A novel metadata analysis approaches for analyzing and understanding wood-decaying mechanisms exhibited by fungi
(2019)Fuel has become an essential commodity in our day to day life. Increase in global population and decreasing fuel reserves have forced mankind to look for other fuel alternatives. Forest biomass serves as a potential renewable ... -
Novel toll-like receptor 4 ligands: synthesis, biological studies and applications in molecular vaccines
(2015-06-15)Lipid A, a unique disaccharide glycolipid, is the active principle of Gram-negative bacterial lipopolysaccharide in activating the innate immune response via Toll-like receptor 4 (TLR4). Given the important role that ... -
Pathogen-host omics analyses of human papillomavirus type 16 sub-lineages in a human epithelial organoid model
(2019)Pathogens such as human papillomaviruses (HPVs) have co-evolved with their hosts and form a molecular basis for common diseases. Persistent infection with the “high-risk” HPV type 16 (HPV16) is a potent cause of anogenital ... -
Physiological adaptations contributing to stress survival in the foodborne pathogen Campylobacter jejuni
(2015-06-15)n spite of being considered fragile and fastidious, the zoonotic pathogen Campylobacter jejuni remains the leading cause of foodborne bacterial gastroenteritis in the developed world. Lacking many of the stress responses ... -
Submerged anaerobic membrane bioreactors for wastewater treatment and membrane fouling characterization and control
(2012-11-10)This thesis focused on effects of transient conditions (pH shocks, temperature variation and temperature shocks) on the performance and membrane fouling characterization and control of submerged anaerobic membrane ...