Browsing Electronic Theses and Dissertations by Title
Now showing items 764-783 of 3484
-
Development of key components of a nitrogen budget for a forested watershed on the Canadian boreal plain
(2009)This investigation, which took place as part of the Forest Watershed and Riparian Disturbance (FORWARD) study in west-central Alberta on the Boreal Plain, measured key components of a nitrogen (N) budget in a relatively ... -
Development of modulators targeting G proteincoupled receptors using a combination of conventional drug discovery methodologies and artificial intelligence techniques
(2023)Lysophosphatidic acid receptor 1 (LPA1) is one of six G protein-coupled receptors (GPCRs) in the LPA receptor family (LPA1-6) and is activated by lysophosphatidic acid (LPA). LPA1 is involved in a wide range of cellular ... -
The development of molecular probes for the in vitro and in vivo study of glucocerebrosidase
(2017)Parkinson’s Disease (PD) is one of the most common neurodegenerative diseases in the world. Despite its prevalence, the disease is difficult to diagnose early with the vast majority of individuals already having significant ... -
Development of multi-probe fluorescence-based assay for boNTA detection
(2015-08-05)Botulinum neurotoxins (BoNTs) cause the lethal disease botulism through the inhibition of acetyl choline secretion by the cleavage of crucial SNARE proteins. Determination of critical residues in the protein sequence of ... -
Development of nanostructured material based electrochemical sensors for food safety and quality control
(2019)The issue of foodborne related illnesses due to additives and contaminants poses a significant challenge to food processing industries. Electrochemical-based strategies offer simple and robust analytical tools, which are ... -
Development of nonlinear 3-D, and novel 2-D optical microscope imaging systems for time-lapse imaging
(2004)The design and development of a nonlinear two-photon, 3-D microscope imaging system, software for manipulation of 2-D and 3-D images, and the operation of a novel 2-D imaging system used for monitoring cultured live cell ... -
Development of optimal breeding zones for white spruce in Ontario under current, past, and anticipated future climate change / by Ashley Marie Thomson.
(2008)Tree breeding zones are delimited areas where trees are selected and bred, and their progeny are planted. Within these zones, the level of adaptation between seedlings and planting sites is controlled to ensure adequate ... -
Development of restrictive disclosure in children's communication with peers
(1986)Research supports the conclusion that adults show a pattern of restrictive disclosure in which they choose to disclose intimate information to friends rather than nonfriends. From a developmental perspective, however, ... -
Development of simulation and machine learning solutions for social issues
(2020)When developing solutions for social issues, it can be difficult to evaluate the impact they may have without a real world implementation. This may not be possible for reasons such as resource, time, and monetary ... -
A device for performing sonoporation on adherent cell cultures
(2015-06-15)Sonoporation is a method for inducing a transient increase in the permeability of cell membranes to otherwise impermeable compounds using ultrasound. This technique has therapeutic potential as it allows for localized ... -
Diagnostic and treatment approaches to fibromyalgia management: quantification of peripheral blood mononuclear cell function and evaluation of radial shockwave therapy
(2019)Fibromyalgia (FM) is a chronic pain disorder that affects many individuals worldwide. The lack of a definitive diagnostic method and highly successful treatment approaches make it an interesting area of research. In the ... -
Diamondiferous mass-flow and traction current deposits in a Neoarchean Fan Delta, Wawa area, Superior Province
(2012-11-10)Diamond bearing Neoarchean metaconglomerates are present in the Michipicoten greenstone belt, Wawa-Abitibi subprovince near Wawa, Ontario. They form a portion of the Dore Metasedimentary rocks in the Arliss Lake subbasin, ... -
Diatoms as an indicator of pharmaceutical contamination in a freshwater system
(2018)Historically, microalgae have been used as bio-indicators of aquatic health and this can be seen in several studies across the world. Often at the bottom of the food chain, microalgae constitute the primary producer of ... -
Dielectric and infrared studies of radio frequency processes in some alcohols
(1988)In this thesis, the results of dielectric studies on a number of aliphatic alcohol molecules with variable chain lengths are presented. This investigation was complemented by infrared and viscosity measurements. Dielectric ... -
Dielectric relaxation and infrared studies of hydrogen bonding
(1985)Dielectric relaxation and infrared study of a number of associating (H-bonding) compounds in glassy media, mainly polystyrene, have been carried out. The dielectric measurements by a General Radio 1621 Precision ... -
Dielectric relaxation studies of some diaryl molecules in polystyrene matrices
(1978)Dielectric relaxation studies of a number of diaryl molecules dispersed in atactic polystyrene and in some cases as solid discs have been carried out. Preparation of the polystyrene matrices and the solid disks, and the ... -
Dielectric studies of molecular and intramolecular motions in polystryrene matrices
(1977)Dielectric absorption studies of a variety of polar solutes containing rotatable groups and of some analogous rigid molecules dispersed in atactic polystyrene have been carried out. Preparation of the solutions as solid ... -
Dielectric studies of molecular motions in some solids
(1982)Dielectric absorption of a number of nonpolar, weakly polar and fairly polar molecules in the pure solid state are studied. Measurements of these solids using either a General Radio 1621 Precision Capacitance Measurement ... -
Dielectric studies of rigid and flexible molecules in various media
(1984)This thesis investigates mainly the molecular and intramolecular relaxation processes of some aromatic and aliphatic molecules containing rotatable polar groups and some analogous rigid molecules dispersed in (a) ...