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The carcinogenic properties of naturally occurring human papillomavirus 16 E6 oncogene variants
Human papillomavirus is the causative agent of the 2nd highest occurring cancer in women, cervical cancer, which is the result of expression of the E6 and E7 oncogenes. Here we challenged the dogma that the oncogenic protein ...
A combined method for establishing keratinocyte cultures from cervical biopsy specimens and creating patent-derived 3-dimensional organotypic raft cultures
High-risk types of human papillomavirus (HPV) are responsible for nearly all instances of cervical cancer, and a significant proportion of head and neck cancers. Studying HPV in the laboratory requires the cultivation of ...