Browsing by Advisor
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18F Radiolabeling of epidermal growth factor receptor-tyrosine kinase inhibitor anti-cancer drugs for therapeutic outcome studies
(2023)Epidermal growth factor receptor is a transmembrane protein with tyrosine kinase activity that plays a vital role in the proliferation, differentiation, and survival of normal cells. When mutations in this protein occur, ... -
Development of an 18F radiolabeling method using solid phase chemistry
(2023)New radiotracers are constantly being developed to expand the clinical applications of positron emission tomography (PET). One of the challenges in the development of PET tracers is the incorporation of a positron emitting ... -
Transition metal ligands for Suzuki-Miyaura cross-coupling reactions and the coordination of radionuclides - studies towards aurora kinase inhibition for PET imaging
(2023)This thesis is wide-ranging covering disparate areas of synthetic organic and metalorganic chemistry, unified by the general use of these projects in medicinal chemistry. Two organometallic palladium complexes 2.3 and ...