Browsing by Committee Member
Now showing items 1-20 of 21
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A longitudinal mitochondrial DNA analysis of modern human hair samples from the Anyang region of China : implications for ancient DNA research
(2003)In 1998, Dr. E. Molto was selected to conduct pilot research on the Hei Heru, Shang Dynasty site in Anyang, China. A major component of this research is the ancient DNA analysis o f human remains recovered at Anyang. ... -
Activity of liposomal taxol against breast cancer cells / by Melanie Heney.
(2007)Taxol (paclitaxel) is one of the most effective chemotherapeutic agents used for the treatment of multiple cancers, including breast, ovarian, and, non-small-cell lung cancer. However, development of taxol resistance with ... -
Adaptive variation in cold hardiness among aspen (Populus tremuloides) provenances
(2002)The relative efficiencies of using different methods to detect genetic variation in cold hardiness were evaluated, and the adaptive variation among aspen provenances was further studied. This thesis is organized as three ... -
The antifeedant action of climacodon septentrionalis and two species of sphaerobolus to hyphal grazing by the fungus-feeding nematode aphelenchoides sp.
(2012-11-10)Fungi are ubiquitous in forest ecosystems and are, collectively, a major force in driving nutrient and organic matter availability and cycling. Some saprotrophic and mycorrhizal fungi are characterized by a perennial ... -
Biological activities of select North American lichens
(2017)The search for novel, pharmacologically significant compounds is a perpetual quest on which biologists, chemists, and bioinformaticians incessantly embark. The sources of these compounds are often of natural origin, making ... -
Characterization of genetic determinants for growth and structure of Listeria monocytogenes biofilms / by Nicholas Choy.
(2007, c200)This thesis investigated wild-type 'Listeria monocytogenes ' EGD and five of its corresponding mutant strains (M1, M4, M7, M11 and M14) for their ability to form biofilms on glass at 22°C and 37°C, with and without shear ... -
Ecology of pathogenic Escherichia coli in water : survival and molecular detection
(2003)Recently there has been a surge of interest in the ability of enterohemmorhagic Escherichia coli (EHEC) to survive in aquatic environments. It has been speculated a correlation may exist between the genotype of an E. ... -
The effects of naturally-derived plant compounds on pseudomonas aeruginosa pathogenicity
(2014-12-12)Pseudomonas aeruginosa has risen as one of the most resistant bacterial pathogens affecting people worldwide. Inefficacy of current antimicrobial treatments to relieve P. aeruginosa infections demands the need for novel ... -
Evaluating DNA Extraction and Analysis of Ancient Seeds: A Study in Peach
(2015)The peach (Prunus persica) is one of the most widely grown stone fruit in the world but its origin and domestication is still being debated. Genetic research has focused on identifying desirable genes for agricultural ... -
Genetic profiling variation caused by tissue type, error, and damage
(2006)Genetic profiling variations caused by tissue type, error, and damage have been studied only minimally in the past. Even though it is well accepted that damage to the DNA molecule and PCR induced error occur, little focus ... -
Identification of genes involved in early endodormancy break in potato tubers
(2013)The growth and harvest of potato tubers for agricultural purposes is important both in Canada and worldwide, and the agronomic importance of this crop is steadily growing. A major issue affecting the storage and transport ... -
The impact of alternate pretreatment methods and osmotic dehydration for the preservation of wild blueberries (Vaccinium angustifolium)
(2018)This study investigated the effects of selected pretreatments and rigorous optimization of osmotic dehydration (OD) of lowbush blueberries using Response Surface Methodology (RSM) to produce dehydrated blueberries with ... -
Improving genetic profiling techniques for low copy number DNA / by Shana Hayter.
(2007)The extraction of DNA from ancient samples presents many obstacles to the analyst. These samples are often subjected to many years of harsh environmental conditions and many forms of damage resulting in low copy number and ... -
The life cycle of human papillomavirus type 16 E6 variants and its effects on the innate immune system of host keratinocytes
(2013-02-01)Persistent infection with human papillomavirus type 16 (HPV16) is the primary aetiological agent for cervical cancer. Viral particles initiate their life cycle by infecting basal keratinocytes of epithelium and amplifying ... -
Lipoic acid and its potential role in the treatment of oxidative-induced injury of A549 lung epithelial cells
(2013-02-01)Oxidative stress is the imbalance between prooxidants and antioxidants within a cell that can cause and/or contribute to the progression of many pathological conditions. Reactive oxygen species (ROS) formed from the ... -
Molecular detection and identification of parasites involved in human disease
(2006)The detection and identification of disease-causing parasites via DNA and the polymerase chain reaction (PCR) offers a new approach for quick and efficient disease diagnosis. Three nucleic acid based technologies have ... -
Reconstructing childhood and adulthood diets from a Caribbean population using stable carbon and nitrogen isotope analysis of dentin and bone collagen
(2012-11-10)The purpose of this study was to establish stable carbon (C) and nitrogen (N) isotope signatures for the 43 individuals in this study population using bone and dentin collagen, and extrapolate the isotopic data to dietary ... -
The Role of free- and liposomal-N-acetycysteine in paraquat-induced cytotoxicity
(2012-11-10)Paraquat (PQ), one of the most commonly used herbicides worldwide, is hightly toxic to humans and exposure can result in severe clinical situations with no effective treatments available. The toxicity of PQ has been ... -
Towards the optimisation of a detection system for markers linked to neural tube defects
(2008)Neural tube defects are the second most common birth defect of the central nervous system. The aim of this research is to design and optimise a novel detection system to analyse five markers that have been shown to be ... -
Transport of Escherichia coli through soil / by Bruce Rosa.
(2007)Sorption is an important process in the retention of pathogens by clay barriers. Batch sorption experiments were conducted to investigate the sorption of nonpathogenic 'E. coli' to illite, kaolinite, and montmorillonite ...
