Browsing by Discipline
Now showing items 21-40 of 50
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Enhancing biomolecule production from Bacillus velezensis PhCL using low-cost agricultural residues as feedstock and improving biomass hydrolysis through enzyme mutagenesis
(2023)Bioproduction have been considered an alternative option for obtaining useful and eco-friendly chemicals for industrial applications. Bacillus velezensis, a trending bacterium first isolated in 2005, is well-known for ... -
Environmental Considerations for Wet Mining Peatlands in Northwestern Ontario
(2012-11-10)Signi cant changes in water quality were detected using a Before-After-Control-Impact (BACI) experimental design. Porewater showed increases in pH, alkalinity, conductivity (including Ca, Mg, K, Na), some metals (Sr, Ba, ... -
Experimental investigation of water entry of a solid object and sand particles
(2023)This thesis presents the results of two different approaches to water entry; first, in Part I, the results of the experimental investigation of the water entry of a solid object, a thick disk in stagnant water, are ... -
Exploration of inflammasomes as targets for therapy of Pseudomonas aeruginosa infection
(2018)Pseudomonas aeruginosa is a common Gram-negative opportunistic bacterial pathogen capable of infecting humans with compromised natural defenses and causing severe pulmonary disease. It is the major cause of severe chronic ... -
Functional Imaging of the Lungs using Magnetic Resonance Imaging of Inert Fluorinated Gases
(2016)Fluorine-19 (19F) magnetic resonance imaging (MRI) of the lungs using inhaled inert fluorinated gases can potentially provide high quality anatomical and functional images of the lungs. This technique is able to visualize ... -
Fundamental studies of microalgal biofilm formation and microalgalbacterial membrane photobioreactors
(2024)Microalgae is one of the photoautotrophic microorganisms that has attracted significant attention in wastewater treatment and biofuel production. Although researchers claimed that microalgae cultivation in wastewater ... -
H2S as a novel biomarker and therapeutic target for asthma
(2015)Asthma is a chronic inflammatory disease with hyper-responsive bronchoconstriction and airway remodeling, leading to extensive airway narrowing. The pathophysiology of asthma remains unclear. The literature shows that the ... -
H2S S-sulfhydration of pyruvate carboxylase in gluconeogenesis and its regulation by Trx1
(2015)Hydrogen sulfide (H2S), regarded as the third gasotransmitter, plays diverse physiological and pathological roles in the body along with another two gasotransmitters, including nitric oxide (NO) and carbon monoxide (CO). ... -
A high throughput screening and characterization of laccase-producing bacterium Serratia quinivorans AORB19 that exhibits lignin degradation traits, dye decolorization efficiency, and enhanced laccase production in biomass
(2023)Laccase (EC 1.10.3.2) assumes a vital role in the degradation of lignin by utilizing oxygen as an oxidant and catalyzing bond cleavage in both phenolic and nonphenolic lignin model compounds. However, their industrial ... -
Humoral immunity in patients with chronic kidney disease and their response to pneumococcal immunization
(2020)In northwestern Ontario the Indigenous First Nations (FN) population have an increased prevalence of chronic kidney disease (CKD). There is an increased rate of infectious disease caused by Streptococcus pneumoniae ... -
Hydrogen sulfide modulates gluconeogenesis and mitochondrial biogenesis in mouse primary hepatocytes
(2016)Among many endogenous substances that regulate hepatic energy production is the gasotransmitter hydrogen sulfide (H2S). In the liver, H2S production is largely catalyzed by cystathionine γ-lyase (CSE) and, to a lesser ... -
Improving Novel Gene Discovery in High-Throughput Gene Expression Datasets
(2012-11-10)High-throughput gene expression datasets (including RNA-seq and microarray datasets) can quantify the expression level of tens of thousands of genes in an organism, which allows for the identification of putative functions ... -
Interaction of lignin derivatives with polymers, ions and soft surfaces in aqueous systems
(2021)Lignin is one of the most abundant biopolymers on earth which has recently gained considerable attention due to its unique potentials to be used in many applications. Many efforts have been made in improving the compatibility ... -
Investigation on anti-proliferative effect of gyrophoric acid from the lichen Umbilicaria muhlenbergii on cancer cells
(2021)Natural products, including primary and secondary metabolites, are small molecules produced by any organism. As important sources of drug components, natural products may be isolated to small fractions with different ... -
Kinetic and thermodynamic studies on pyrolysis of waste HDPE polymers
(2017)Pyrolysis is a promising technology for converting waste plastic into high-value hydrocarbons, which can help to protect the environment and improve the waste management industry. Available methods for finding kinetic ... -
Lignin-based flocculant and dispersant for wastewater treatment
(2018)The wastewaters produced from different industries contain fine and charged suspended particles and other impurities. Today, the removal of these colloidal particles from the wastewater has become a serious challenge for ... -
Long term DNA storage evaluation and methodology
(2021)DNA preservation over the long term is a considerable problem for many fields that still lack a viable, cost-effective, long-term solution. The considerable amount of genetic material that is currently aging in facilities ... -
Metal induced olfactory impairment in fish: gene expression, protection and recovery
(2014)To play their ecological role in an ecosystem, a fully functioning olfactory system is vital for fishes. A fish's olfactory system is very sensitive to low concentrations of contaminants. A great deal of research has ... -
Microbial production of value-added products from wood hemicellulose prehydrolysate
(2020)Hemicellulose, the second most abundant polymer in nature, has the great potential to be used for the production of biochemicals under the concept of biorefining. As hemicellulose is watersoluble, it can also be easily ... -
Modelling the molecular mechanisms of biocompatibility of artifical materials
(2015)One of the most common reasons for implant failure is immune rejection. Implant rejection leads to additional surgical intervention and, ultimately, increases health cost as well as recovery time. Within a few hours after ...