Browsing by Committee Member
Now showing items 1-20 of 28
-
Assessing in vitro DNA repair methods / by Ryan Lehto.
(2010)The DNA molecule is constantly under attack from endogenous and exogenous sources leading to degradation by a variety of forms of damage. In this study current methods of in vitro DNA repair methods were evaluated for ... -
Bacterial isolation and bioconversion of organic materials to industrial platform chemicals
(2018)Careful selection/isolation of the suitable microbial consortium for enzymatic saccharification of organic matters is a critical step in biofuels production. We isolated strains EF2, OW1-1 and HK2 from intestine of Eisenia ... -
Bioremediation of contaminated soils from mine sites using native plants in Northwestern Ontario
(2016)Practical and scientific importance can be found in this research topic since the results directly apply to remediation of industrial and mined lands in the boreal forest region. Plants suitable for phytostabilization of ... -
Campylobacter jejuni : biofilm formation and oxidative stress
(2009)Campylobacter jejuni (C. jejuni) is a zoonotic pathogen most often associated with poultry and the leading cause of bacterial gastroenteritis in the developed world. It is an obligate microaerobe, requiring low levels of ... -
The cumulative effects of hypoxia and hyperglycemia on cardiac oxidative stress
(2014-01-22)Hyperglycaemia-induced oxidative stress plays an important role in cardiomyocyte cell death leading to cardiac dysfunction. Autophagy is an intracellular bulk degradation process and can be induced by stressors such as ... -
Cystathionine gamma-lyase/hydrogen sulfide system and glucose homeostasis
(2013-02-12)Research in the last twenty years has transformed the role of hydrogen sulfide (H2S) being perceived from a toxic gas to a gaso-transmitter with diverse physiological and pathological significance. Cystathionine gamma-lyase ... -
Detection and characterization of DNA damage
(2009)The DNA molecule is constantly subjected to endogenous and exogenous sources of damage which if left unrepaired can lead to genotoxic and cytotoxic outcomes. These lesions have been implicated in the development of numerous ... -
Effects of feed and operating conditions on the performance and membrane fouling of a submerged anaerobic membrane bioreactor
(2012)Anaerobic membrane bioreactors (AnMBRs) have been recognized as an effective method for enhanced wastewater treatment and re-use. However, the loss of the membrane performances due to membrane fouling remains a major ... -
The effects of naturally-derived plant compounds on pseudomonas aeruginosa pathogenicity
(2014-12-12)Pseudomonas aeruginosa has risen as one of the most resistant bacterial pathogens affecting people worldwide. Inefficacy of current antimicrobial treatments to relieve P. aeruginosa infections demands the need for novel ... -
Efficacy of bacteria and caffeine as indicators of anthropogenic waste in freshwater systems
(2018)With urban sprawl and intensified agriculture, nutrient loading of waterways has become a pressing issue across southern Ontario. Domestic wastes are more likely than other wastewater sources to be associated with the ... -
Enhancing biomolecule production from Bacillus velezensis PhCL using low-cost agricultural residues as feedstock and improving biomass hydrolysis through enzyme mutagenesis
(2023)Bioproduction have been considered an alternative option for obtaining useful and eco-friendly chemicals for industrial applications. Bacillus velezensis, a trending bacterium first isolated in 2005, is well-known for ... -
Environmental Considerations for Wet Mining Peatlands in Northwestern Ontario
(2012-11-10)Signi cant changes in water quality were detected using a Before-After-Control-Impact (BACI) experimental design. Porewater showed increases in pH, alkalinity, conductivity (including Ca, Mg, K, Na), some metals (Sr, Ba, ... -
Evaluating DNA Extraction and Analysis of Ancient Seeds: A Study in Peach
(2015)The peach (Prunus persica) is one of the most widely grown stone fruit in the world but its origin and domestication is still being debated. Genetic research has focused on identifying desirable genes for agricultural ... -
Evaluation of Anti-E6 Single Domain Antibodies for the Treatment of Human Papillomavirus-related Cancer
(2022)The HPV16 genome encodes two oncoproteins, E6 and E7, which are essential for viral carcinogenesis. While E7 promotes cell proliferation, E6 abolishes the resulting p53-dependent apoptotic response. We hypothesized that ... -
Exploration of inflammasomes as targets for therapy of Pseudomonas aeruginosa infection
(2018)Pseudomonas aeruginosa is a common Gram-negative opportunistic bacterial pathogen capable of infecting humans with compromised natural defenses and causing severe pulmonary disease. It is the major cause of severe chronic ... -
Expression of T4 lysozyme gene in escherichia coli and trichoderma reesei
(2014-01-22)The T4 lysozyme, from bacteriophage T4, has the ability to lyse bacterial cell walls; thus it has attracted immense attention as an antimicrobial agent. Nonetheless, the production of T4L cannot meet our needs. All of the ... -
Geochemical and toxicological investigation of the Hogarth and Caland Pit Lakes, former Steep Rock Iron Mine site
(2012-11-10)The closure of the Steep Rock Iron Mines near Atikokan, Ontario, Canada in the late 1970's left behind an area of severe environmental concern. The subsequent flooding of the pit mines resulted in the formation of two ... -
Isolation and characterization of novel cellulase and pectinase producing bacteria
(2015)Cellulases and pectinases are the major cell wall degrading enzymes. The microorganisms producing these enzymes have a wide range of industrial applications. In this research, 17 bacterial isolates from rotting wood ... -
Nanomaterial-based Electrochemical Sensors for the Detection of Glucose and Cholesterol
(2011)Electrochemical detection methods are highly attractive for the monitoring of glucose, cholesterol, cancer, infectious diseases, and biological warfare agents due to their low cost, high sensitivity, functionality despite ... -
Northern wild rice (Zizania palustris L.) as a phytoremediation species in eutrophic wetlands - investigation of root-sediment interactions
(2014-01-22)The causes of anthropogenic eutrophication in water bodies are multi-faceted and multigenerational, presenting an ever increasing need for effective and sustainable solutions.Phytoremediation presents a cost-effective ...