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Cross-talk of hydrogen sulfide and nitric oxide in vascular endothelial cells
(2014)Gasotransmitters, like hydrogen sulfide (H2S) and nitric oxide (NO), are small gaseous molecules that can be generated in different types of mammalian cells by enzymatic catalyzation. Cystathionine y-lyase (CSE) and ... -
Cystathionine gamma-lyase/hydrogen sulfide system and glucose homeostasis
(2013-02-12)Research in the last twenty years has transformed the role of hydrogen sulfide (H2S) being perceived from a toxic gas to a gaso-transmitter with diverse physiological and pathological significance. Cystathionine gamma-lyase ... -
Cystathionine γ-lyase and hypoxia : implicating hydrogen sulfide in the hypoxic stress response
(2012-11-10)Hydrogen sulfide (H2 S) has emerged as a novel and important gasotransmitter for the cardiovascular system, where it is generated mainly by cystathionine γ-lyase (CSE). Abnormal metabolism and functions of the H2 S/CSE ... -
H2S as a novel biomarker and therapeutic target for asthma
(2015)Asthma is a chronic inflammatory disease with hyper-responsive bronchoconstriction and airway remodeling, leading to extensive airway narrowing. The pathophysiology of asthma remains unclear. The literature shows that the ... -
H2S S-sulfhydration of pyruvate carboxylase in gluconeogenesis and its regulation by Trx1
(2015)Hydrogen sulfide (H2S), regarded as the third gasotransmitter, plays diverse physiological and pathological roles in the body along with another two gasotransmitters, including nitric oxide (NO) and carbon monoxide (CO). ... -
Hydrogen sulfide modulates gluconeogenesis and mitochondrial biogenesis in mouse primary hepatocytes
(2016)Among many endogenous substances that regulate hepatic energy production is the gasotransmitter hydrogen sulfide (H2S). In the liver, H2S production is largely catalyzed by cystathionine γ-lyase (CSE) and, to a lesser ...