Browsing by Discipline
Now showing items 1-14 of 14
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Amorphous lead oxide (a-PbO) for direct conversion X-ray imaging detectors
(2022)Modern medical imaging revolutionized the way that medical conditions are diagnosed. It became possible after significant advancements in science and technology related to the medical visualization field. X-ray imaging ... -
Catastrophe theory, symmetry breaking and the pseudo Jahn-Teller effect
(2019)This research focuses on the structural symmetry breaking observed in hypovalent silicon containing compounds. The structural symmetry breaking was studied from the perspective of the pseudo Jahn-Teller effect (pJTE). A ... -
Design, synthesis, and evaluation of novel aurora kinase inhibitors for cancer diagnosis and therapy
(2024)Cancer is the second leading cause of death globally. Advances in cancer diagnosis and therapeutics plays a critical role in global health and a patient’s life. Aurora kinases, as mitotic kinases, regulate multiple mitotic ... -
Development of modulators targeting G proteincoupled receptors using a combination of conventional drug discovery methodologies and artificial intelligence techniques
(2023)Lysophosphatidic acid receptor 1 (LPA1) is one of six G protein-coupled receptors (GPCRs) in the LPA receptor family (LPA1-6) and is activated by lysophosphatidic acid (LPA). LPA1 is involved in a wide range of cellular ... -
Electrochemical reduction of carbon dioxide on nanostructured catalysts
(2018)There is great interest in the conversion of carbon dioxide (CO2) to useful chemicals and fuels toward addressing the increasingly serious impacts of global climate change. The electrochemical reduction of CO2 has garnered ... -
Fabrication, characterization and electrochemical studies of nickel and nickel-based materials
(2017)Nickel is a naturally abundant transition metal and is very cost effective. This, along with mechanical and magnetic characteristics, and good catalytic activity in different applications, has made it an interesting non-noble ... -
Fiber laser system for the detection of trace gas
(2017)The research presented in this thesis is on the development of a trace gas detection system based on intracavity absorption spectroscopy (ICAS). The developed system was capable of detecting nitrous oxide (N2O) and acetylene ... -
Lead oxide (PbO) for direct conversion detectors
(2017)There is great interest in the utilization of non-crystalline photoconductors for direct conversion medical X-ray imaging detectors. Lead Oxide (PbO) is one of the most promising candidates for application in general ... -
Medical applications of fluorine-19 and hyperpolarized xenon129 magnetic resonance imaging
(2020)Multinuclear magnetic resonance imaging (MRI) is currently under extensive development. Although conventional proton MRI is mostly known as an anatomical medical imaging modality with an excellent soft tissue contrast, ... -
The medical applications of hyperpolarized Xe and nonproton magnetic resonance imaging
(2024)Hyperpolarized 129Xe (HP 129Xe) magnetic resonance imaging (MRI) is a relatively young field which is experiencing significant advancements each year. Conventional proton MRI is widely used in clinical practice as an ... -
Segmented hollow core photonic crystal fiber as a gas cell
(2022)Developing a unique gas cell based on hollow core photonic crystal fiber (HC- PCF) improving its ability to be used in measurements which require higher temporal resolution. Traditional HC-PCF is an excellent candidate ... -
Substituent descriptors from the topology of the electron density
(2021)This work focuses on determining the suitability of functional group properties from the Quantum Theory of Atoms in Molecules (QTAIM) as descriptors for use in machine learning and linear regression analyses. These were ... -
Transition metal ligands for Suzuki-Miyaura cross-coupling reactions and the coordination of radionuclides - studies towards aurora kinase inhibition for PET imaging
(2023)This thesis is wide-ranging covering disparate areas of synthetic organic and metalorganic chemistry, unified by the general use of these projects in medicinal chemistry. Two organometallic palladium complexes 2.3 and ... -
Valorization of Kraft lignin via alkaline and acid- mediated aerobic oxidation processes
(2023)Lignin is a complex heterogeneous aromatic compound derived from renewable plant biomass. Due to its aromatic backbone, it has grown interested in producing biochemicals and other polymeric applications. Depending on the ...
