Please use this identifier to cite or link to this item:
https://knowledgecommons.lakeheadu.ca/handle/2453/709
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | Yang, Guangdong | |
dc.contributor.advisor | Wang, Rui | |
dc.contributor.author | Ju, YoungJun | |
dc.date.accessioned | 2016-01-11T19:01:16Z | |
dc.date.available | 2016-01-11T19:01:16Z | |
dc.date.created | 2015 | |
dc.date.issued | 2015 | |
dc.identifier.uri | http://knowledgecommons.lakeheadu.ca/handle/2453/709 | |
dc.description.abstract | Hydrogen sulfide (H2S), regarded as the third gasotransmitter, plays diverse physiological and pathological roles in the body along with another two gasotransmitters, including nitric oxide (NO) and carbon monoxide (CO). In the liver, cystathionine gamma-lyase (CSE) is the main enzyme to generate H2S. The functions of H2S in the liver are largely unknown even though many studies showed H2S and CSE are important in redox control of liver. S-sulfhydration, a novel post-translational modification of proteins, is now considered as an important mechanism of H2S effects under various physiological and pathological conditions. | en_US |
dc.language.iso | en_US | en_US |
dc.subject | Gasotransmitters | en_US |
dc.subject | Hydrogen sulfide | en_US |
dc.subject | Pyruvate carboxylase | en_US |
dc.subject | Thioredoxin 1 | en_US |
dc.title | H2S S-sulfhydration of pyruvate carboxylase in gluconeogenesis and its regulation by Trx1 | en_US |
dc.type | Dissertation | |
etd.degree.name | Doctor of Philosophy | en_US |
etd.degree.level | Doctoral | en_US |
etd.degree.discipline | Biotechnology | en_US |
etd.degree.grantor | Lakehead University | en_US |
dc.contributor.committeemember | Khaper, Neelam | |
dc.contributor.committeemember | Qin, Wensheng | |
Appears in Collections: | Electronic Theses and Dissertations from 2009 |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
JuY2015d-1a.pdf | 4.1 MB | Adobe PDF | ![]() View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.