Browsing by Advisor
Now showing items 1-5 of 5
-
18F Radiolabeling of epidermal growth factor receptor-tyrosine kinase inhibitor anti-cancer drugs for therapeutic outcome studies
(2023)Epidermal growth factor receptor is a transmembrane protein with tyrosine kinase activity that plays a vital role in the proliferation, differentiation, and survival of normal cells. When mutations in this protein occur, ... -
Application of flow-through sold-phase-synthesis to the fluorescent labeling of amines with carboxylic and funtionalized bodipy dyes
(2024)The use of fluorophores for the labelling of biomolecules in living cells has become a key method for understanding processes in cellular biology. Synthetic fluorescent molecules can be introduced non-specifically to ... -
Development of an 18F radiolabeling method using solid phase chemistry
(2023)New radiotracers are constantly being developed to expand the clinical applications of positron emission tomography (PET). One of the challenges in the development of PET tracers is the incorporation of a positron emitting ... -
Enantioselective cross-coupling of monosubstituted ferrocenes in chiral ionic liquids
(2024)Planarly chiral ferrocenes have applications in pharmaceuticals, agrochemicals, and biomedical research for their use as ligands or catalysts in asymmetric synthesis. Previous methods of enantioselective synthesis of ... -
Transition metal ligands for Suzuki-Miyaura cross-coupling reactions and the coordination of radionuclides - studies towards aurora kinase inhibition for PET imaging
(2023)This thesis is wide-ranging covering disparate areas of synthetic organic and metalorganic chemistry, unified by the general use of these projects in medicinal chemistry. Two organometallic palladium complexes 2.3 and ...
