Browsing by Advisor
Now showing items 1-13 of 13
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The antioxidant resveratrol down-regulates inflammation in an in vitro model of Pseudomonas aeruginosa infection of lung epithelial cells
(2014-01-22)Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen capable of infecting the lungs and causing severe pulmonary disease in immunocompromised individuals. During the infectious process, P. aeruginosa provokes ... -
Biological studies of muramyl dipeptide analogues as potential ligands for NOD2 receptor
(2023)The human body’s survival against various foreign disease-causing organisms solely depends on the protection provided by our body's immune system. Our body's complex yet effective immune system comprises cells, molecules ... -
Exploration of inflammasomes as targets for therapy of Pseudomonas aeruginosa infection
(2018)Pseudomonas aeruginosa is a common Gram-negative opportunistic bacterial pathogen capable of infecting humans with compromised natural defenses and causing severe pulmonary disease. It is the major cause of severe chronic ... -
Expression of integrin and toll-like receptors in cervical cancer (in vivo and ex vivo study)
(2009)Cervical cancer is the second most common cancer in women world-wide. Although persistent human papillomavirus (HPV) infection is considered the most important causative agent of cervical cancer, the mechanisms toward ... -
Humoral immunity in patients with chronic kidney disease and their response to pneumococcal immunization
(2020)In northwestern Ontario the Indigenous First Nations (FN) population have an increased prevalence of chronic kidney disease (CKD). There is an increased rate of infectious disease caused by Streptococcus pneumoniae ... -
The Incidence of invasive Haemophilus influenzae disease in Northwestern Ontario
(2009)Prior to the late 1980s, Haemophilus influenzae type b (Hib) was the most common cause of meningitis, epiglottitis, and other invasive bacterial infections in young children. The introduction of the conjugate Hib vaccines ... -
Neutrophils in the interface between innate and adaptive immunity in response to Haemophilus influenzae type a
(2022)Haemophilus influenzae type a (Hia) is a bacterial human pathogen that has emerged as a significant cause of invasive disease in Canadian Indigenous populations. Protection against encapsulated bacteria such as Hia is ... -
Novel toll-like receptor 4 ligands: synthesis, biological studies and applications in molecular vaccines
(2015-06-15)Lipid A, a unique disaccharide glycolipid, is the active principle of Gram-negative bacterial lipopolysaccharide in activating the innate immune response via Toll-like receptor 4 (TLR4). Given the important role that ... -
Role of haemophilus influenzae lipooligosaccharide in the activation of innate and adaptive immunity
A Gram negative human bacterial pathogen Haemophilus influenzae expresses a truncated endotoxin known as lipooligosaccharide (LOS). Recent studies on H. influenzae LOS have highlighted its structural and compositional ... -
Study of host pathogen interactions using a model of Pseudomonas aeruginosa infection of lung epithelial cells / by Rebecca Barnes.
(2008)Pseudomonas aeruginosa is an opportunistic pulmonary pathogen that can cause acute, life-threatening pneumonia in immunocompromised individuals, it is a common cause of high-mortality ventilator associated pneumonia, and ... -
Study of the activation of the inflammasome protein complex by Haemophilus influenzae Type a
(2021)Haemophilus influenzae (Hi) is a gram-negative bacterium capable of causing severe invasive infection such as meningitis and is classified by the presence or absence of polysaccharide capsule. The polysaccharide capsule ... -
Utility of the theory of planned behaviour in health services research when examining the intentions of immunization provider behaviour
(2009)This paper will demonstrate the need for public health involvement with health services research in order to effectively meet its' mandate for achieving population health. The success of our public health programs requires ... -
West Nile virus (WNv) human vaccine : from research to vaccination
(2007)This project will educate readers about the West Nile virus (WNv), and the vaccine research approaches currently underway. A narrative review used an instrument to synthesize WNv vaccine research studies, into an ...
