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Medical applications of fluorine-19 and hyperpolarized xenon129 magnetic resonance imaging
(2020)
Multinuclear magnetic resonance imaging (MRI) is currently under extensive
development. Although conventional proton MRI is mostly known as an anatomical medical
imaging modality with an excellent soft tissue contrast, ...
Amorphous lead oxide (a-PbO) for direct conversion X-ray imaging detectors
(2022)
Modern medical imaging revolutionized the way that medical conditions are diagnosed. It became
possible after significant advancements in science and technology related to the medical
visualization field. X-ray imaging ...
Substituent descriptors from the topology of the electron density
(2021)
This work focuses on determining the suitability of functional group
properties from the Quantum Theory of Atoms in Molecules (QTAIM) as
descriptors for use in machine learning and linear regression analyses.
These were ...
Segmented hollow core photonic crystal fiber as a gas cell
(2022)
Developing a unique gas cell based on hollow core photonic crystal fiber (HC-
PCF) improving its ability to be used in measurements which require higher temporal
resolution. Traditional HC-PCF is an excellent candidate ...
Valorization of Kraft lignin via alkaline and acid- mediated aerobic oxidation processes
(2023)
Lignin is a complex heterogeneous aromatic compound derived from renewable plant biomass.
Due to its aromatic backbone, it has grown interested in producing biochemicals and other
polymeric applications. Depending on the ...
Development of modulators targeting G proteincoupled receptors using a combination of conventional drug discovery methodologies and artificial intelligence techniques
(2023)
Lysophosphatidic acid receptor 1 (LPA1) is one of six G protein-coupled receptors (GPCRs) in
the LPA receptor family (LPA1-6) and is activated by lysophosphatidic acid (LPA). LPA1 is
involved in a wide range of cellular ...
Transition metal ligands for Suzuki-Miyaura cross-coupling reactions and the coordination of radionuclides - studies towards aurora kinase inhibition for PET imaging
(2023)
This thesis is wide-ranging covering disparate areas of synthetic organic and metalorganic
chemistry, unified by the general use of these projects in medicinal chemistry.
Two organometallic palladium complexes 2.3 and ...