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In vitro antioxidant and antibacterial activity of twenty-one Northern Ontario medicinal plants
Aboriginal communities in the northern Ontario region utilize an abundance of locally grown medicinal plants. However, no prior documentation or phytochemical studies on the northern Ontario medicinal plants existed in ...
The cumulative effects of hypoxia and hyperglycemia on cardiac oxidative stress
Hyperglycaemia-induced oxidative stress plays an important role in cardiomyocyte cell death leading to cardiac dysfunction. Autophagy is an intracellular bulk degradation process and can be induced by stressors such as ...
The effect of Omega-3 polyunsaturated fatty acid supplementation on lipid composition, oxidative stress, and aldehyde concentrations in rat liver and brain
Oxidative stress is caused by an imbalance between the production and removal of reactive oxygen species (ROS). Polyunsaturated fatty acids (PUFA), due to their multiple carbon-carbon double bonds, react readily with ROS ...
Cystathionine γ-lyase and hypoxia : implicating hydrogen sulfide in the hypoxic stress response
Hydrogen sulfide (H2 S) has emerged as a novel and important gasotransmitter for the cardiovascular system, where it is generated mainly by cystathionine γ-lyase (CSE). Abnormal metabolism and functions of the H2 S/CSE ...
Secoisolariciresinol diglucoside reduces cell death and upregulates antioxidants in cardiac iron overload
Iron is essential to many biological and metabolic processes used in all organisms, but excess iron can result in complications such as cirrhosis, diabetes, and heart failure. Cardiac iron overload has been linked to ...
Lipoic acid and its potential role in the treatment of oxidative-induced injury of A549 lung epithelial cells
Oxidative stress is the imbalance between prooxidants and antioxidants within a cell that can cause and/or contribute to the progression of many pathological conditions. Reactive oxygen species (ROS) formed from the ...