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Design and evaluation of novel fluorescent molecular probes targeting cathepsin B
(2020)
Lysosomal cysteine proteinase cathepsin B (CTB) is a member of the cysteine protease family
known to participate in intracellular degradation processes and protein turnover in the lysosomes
of healthy cells. Cathepsin B ...
Humoral immunity in patients with chronic kidney disease and their response to pneumococcal immunization
(2020)
In northwestern Ontario the Indigenous First Nations (FN) population have an increased
prevalence of chronic kidney disease (CKD). There is an increased rate of infectious disease
caused by Streptococcus pneumoniae ...
Interaction of lignin derivatives with polymers, ions and soft surfaces in aqueous systems
(2021)
Lignin is one of the most abundant biopolymers on earth which has recently gained considerable
attention due to its unique potentials to be used in many applications. Many efforts have been made
in improving the compatibility ...
Carboxyalkylated cullulose nanocrystals for novel applications
(2021)
Cellulose nanocrystals (CNC), rigid rod-like nanoparticles, are derived from cellulose through acid
hydrolysis and are considered as emerging nanomaterials according to their beneficial properties
and commercial availability. ...
Microbial production of value-added products from wood hemicellulose prehydrolysate
(2020)
Hemicellulose, the second most abundant polymer in nature, has the great potential to be used for
the production of biochemicals under the concept of biorefining. As hemicellulose is watersoluble, it can also be easily ...
Adipose tissue remodeling in response to corticosterone and β3-adrenergic receptor agonist mirabegron
(2022)
With the rise of metabolic diseases including obesity and type 2 diabetes, the need to investigate one
of the most dynamic endocrine organs is critical for combating these diseases. Adipose tissue (AT) exists
predominantly ...
Investigation on anti-proliferative effect of gyrophoric acid from the lichen Umbilicaria muhlenbergii on cancer cells
(2021)
Natural products, including primary and secondary metabolites, are small molecules produced by
any organism. As important sources of drug components, natural products may be isolated to small
fractions with different ...
Long term DNA storage evaluation and methodology
(2021)
DNA preservation over the long term is a considerable problem for many fields that still
lack a viable, cost-effective, long-term solution. The considerable amount of genetic material
that is currently aging in facilities ...
Characterization of novel cellulase and glucose isomerase-producing bacteria and optimization of the enzyme production conditions and their potential applications in environment and industry
(2022)
Cellulases and glucose isomerases are vital enzymes in converting cellulose into fructose.
Cellulases catalyze cellulose conversion to glucose, while glucose isomerase catalyzes the
reversible isomerization of glucose ...
Electrokinetic-assisted membrane photobioreactor (EK-MPBR) for municipal wastewater treatment
(2023)
Membrane technology and phycoremediation, which utilizes algae for nutrient removal, are two
major emerging technologies for wastewater treatment. Membrane photobioreactors (MPBRs)
integrate these technologies and provide ...