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Design, synthesis, and evaluation of novel lysophosphatidic acid receptor-targeting small molecules as therapeutic and diagnostic agents
(2023)
Breast cancer has the highest incidence rate of all cancers among Canadian women and
accounts for nearly 14% of all cancer-related deaths in Canada. This type of cancer is often
detected using medical imaging modalities ...
Development of an 18F radiolabeling method using solid phase chemistry
(2023)
New radiotracers are constantly being developed to expand the clinical applications of
positron emission tomography (PET). One of the challenges in the development of PET tracers
is the incorporation of a positron emitting ...
18F Radiolabeling of epidermal growth factor receptor-tyrosine kinase inhibitor anti-cancer drugs for therapeutic outcome studies
(2023)
Epidermal growth factor receptor is a transmembrane protein with tyrosine kinase activity that plays a vital role in the proliferation, differentiation, and survival of normal cells. When mutations in this protein occur, ...