Browsing Electronic Theses and Dissertations from 2009 by Title
Now showing items 322-341 of 1540
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Design and synthesis of small molecule ligands targeting protease-activated receptor 2 as potential diagnostic and therapeutic agents
(2021)Positron emission tomography (PET) imaging requires radionuclides (positron-emitters) labeled molecules (tracers) to image biochemical and physiological processes in vivo and helps diagnose diseases noninvasively. The ... -
Design and testing of a permeable reactive barrier system for treatment of sulphate rich waters at the former steep rock iron mine, Atikokan, Ontario
(2015)Acid mine drainage (AMD) is one of the greatest challenges facing the mining industry globally. Methods for addressing this issue have been widely studied; however, few studies have addressed sites with a less common water ... -
Design methodology for Class D ultrasound transducer drivers
(2021)Ultrasound refers to sound waves with frequencies above the upper limit of human hearing. Due to the high frequency, the energy can be concentrated and used for therapeutic applications, such as ultrasound imaging ... -
A Design Methodology for Low Power CMOS Current Source
(2016)A current reference circuit is a basic building block in analog, digital and mixed-signal design systems. This work focuses on one type of integrated CMOS current reference circuit. This source only uses one type of ... -
Design of a beam-steerable microstrip line based leaky wave antenna using uniaxial field programmable microwave substrate (FPMS)
(2021)The ever-growing wireless technologies of today are pushing the limits of the state-of-the-art radio frequency (RF) components design. One special requirement which is widely needed in modern applications is for the RF ... -
Design of polarization reconfigurable beam-steerable and frequency tunable FPMS based SIW-slot antennas
(2022)With the rapid evolution of modern and smart communication technologies such as 5th generation of mobile network (5G), (internet of things) IoT, Autonomous Vehicles, Aviation Technology, etc., the need for reconfigurable ... -
The design of Zr metal-organic frameworks in the detection and neutralization of organophosphorus based nerve agents and pesticides
(2022)Organophosphates are ubiquitous in uses ranging from chemical warfare agents (CWA’s) to detergents. In between these two extreme uses lie organophosphorus-based agrichemicals, primarily pesticides, which are applied in ... -
Design, development and usability evaluation of social system interface and development of computational model
(2021)In recent times, methods of computational intelligence (CI) that aim to solve real-life problems are developed by computer science researchers in collaboration with domain experts. There has also been an increased emphasis ... -
Design, simulation and control of a 12 DOF biped robot
(2012-11-10)The field of humanoid robotics has in the last several decades taken off as an active area of research. The goal of this field id to build robots which by having a human-like form will be able to work in environments ... -
The design, synthesis and enzymatic evaluation of aminocyclitol inhibitors of glucocerebrosidase
(2014-01-22)Gaucher disease, the most common lysosomal storage disorder, is caused by mutations in the GBA gene which codes for the enzyme glucocerebrosidase (GCase) resulting in its deficiency. GCase deficiency results in the ... -
Design, synthesis, and evaluation of novel lysophosphatidic acid receptor-targeting small molecules as therapeutic and diagnostic agents
(2023)Breast cancer has the highest incidence rate of all cancers among Canadian women and accounts for nearly 14% of all cancer-related deaths in Canada. This type of cancer is often detected using medical imaging modalities ... -
Detecting Crohn’s disease from high resolution endoscopy videos: the thick data approach
(2023)Detecting diseases in high resolution endoscopy videos can be done in several ways depending on the methodology for detection. One such method that has been a hot topic in the field of medical technology research is the ... -
Detection and characterization of DNA damage
(2009)The DNA molecule is constantly subjected to endogenous and exogenous sources of damage which if left unrepaired can lead to genotoxic and cytotoxic outcomes. These lesions have been implicated in the development of numerous ... -
Detection of Deoxyribonucleic Acid Damage Induced by Metal Ion Interactions and Repair of Metal Ion Deoxyribonucleic Acid Cross-links
(2010-08-17)There are many forms of DNA damage. One of these, DNA-metal cross-links are particularly problematic as they not only affect the tautomeric structure of DNA, but can also inhibit enzymatic activity and block amplification ... -
Detection, identification, and mitigation of false data injection attacks and faults in vehicle platooning
(2023)Smart vehicles are designed leveraging advanced hardware, including sensors, and cuttingedge technologies, such as artificial intelligence, Vehicle-to-Vehicle (V2V) communication, and Vehicle-to-Infrastructure (V2I) ... -
Determining the "spread of effects" of physical activity interventions from children to Parents/Guardians
(2014-01-22)The purpose of this research was to determine whether parental involvement in a physical activity intervention delivered to children in-school could result in positive behaviour change in parents (“spread of effects”), as ... -
Determining the predictability of acute mountain sickness using a regression analysis
(2010)AMS (Acute Mountain Sickness) is an altitude-related illness that occurs as a direct result of hypoxia. To date there is no consistent diagnostic measurement tool, leaving AMS as a subjectively-measured illness. An exploratory ... -
Determining the strongest predictor of FAST aerobic fitness
(2009)Ice hockey is a unique sport requiring a combination of well developed fitness capacities that can be generally referred to as 'ice hockey fitness'. To be successful at a representative level an ice hockey player must have ... -
Developing a collaborative MOOC learning environment utilizing video sharing with discussion summarization as added-value
(2015-06-16)With the fast-growing Massive Open Online Courses (MOOC) community and the increase in the number of Learning Management Systems (LMSs) available online, the amount of shared information is massive. Current LMS - in ... -
Developing a Multiplex PCR Platform to Determine the Virulence Genes of Escherichia Coli in Boulevard Lake, Thunder Bay, Ontario
Given the evidence that E. coli can establish in the periphytic community and be released back into the water column, it is important to understand the pathogenicity of this group of E. coli by examining the virulence genes ...