Lakehead University Library Logo
    • Login
    View Item 
    •   Knowledge Commons Home
    • Electronic Theses and Dissertations
    • Electronic Theses and Dissertations from 2009
    • View Item
    •   Knowledge Commons Home
    • Electronic Theses and Dissertations
    • Electronic Theses and Dissertations from 2009
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.
    quick search

    Browse

    All of Knowledge CommonsCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsDisciplineAdvisorCommittee MemberThis CollectionBy Issue DateAuthorsTitlesSubjectsDisciplineAdvisorCommittee Member

    My Account

    Login

    Statistics

    View Usage Statistics

    H2S S-sulfhydration of pyruvate carboxylase in gluconeogenesis and its regulation by Trx1

    Thumbnail

    View/Open

    JuY2015d-1a.pdf (4.007Mb)

    Date

    2015

    Author

    Ju, YoungJun

    Degree

    Doctor of Philosophy

    Discipline

    Biotechnology

    Subject

    Gasotransmitters
    Hydrogen sulfide
    Pyruvate carboxylase
    Thioredoxin 1

    Metadata

    Show full item record

    Abstract

    Hydrogen sulfide (H2S), regarded as the third gasotransmitter, plays diverse physiological and pathological roles in the body along with another two gasotransmitters, including nitric oxide (NO) and carbon monoxide (CO). In the liver, cystathionine gamma-lyase (CSE) is the main enzyme to generate H2S. The functions of H2S in the liver are largely unknown even though many studies showed H2S and CSE are important in redox control of liver. S-sulfhydration, a novel post-translational modification of proteins, is now considered as an important mechanism of H2S effects under various physiological and pathological conditions.

    URI

    http://knowledgecommons.lakeheadu.ca/handle/2453/709

    Collections

    • Electronic Theses and Dissertations from 2009

    Lakehead University Library
    Contact Us | Send Feedback

     


    Lakehead University Library
    Contact Us | Send Feedback