Browsing by Committee Member
Now showing items 1-7 of 7
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Cross-coupling reactions: synthesis and photoactivity of enediynes
(2015-02-02)The syntheses of a number of photoactive enediynes using the Sonogashira Coupling reaction are described. Alkynes with different characteristics were coupled to 2-bromoiodobenzene to yield the desired drugs. The enediyne’s ... -
Design, synthesis, and evaluation of novel aurora kinase inhibitors for cancer diagnosis and therapy
(2024)Cancer is the second leading cause of death globally. Advances in cancer diagnosis and therapeutics plays a critical role in global health and a patient’s life. Aurora kinases, as mitotic kinases, regulate multiple mitotic ... -
Electrochemical reduction of carbon dioxide on nanostructured catalysts
(2018)There is great interest in the conversion of carbon dioxide (CO2) to useful chemicals and fuels toward addressing the increasingly serious impacts of global climate change. The electrochemical reduction of CO2 has garnered ... -
Expression of T4 lysozyme gene in escherichia coli and trichoderma reesei
(2014-01-22)The T4 lysozyme, from bacteriophage T4, has the ability to lyse bacterial cell walls; thus it has attracted immense attention as an antimicrobial agent. Nonetheless, the production of T4L cannot meet our needs. All of the ... -
Isolation and characterization of bioconversion microbes and aerobic conversion of crude glycerol to value-added bioproducts
(2018)Renewable forms of energy are of significant interest in today’s economies. Biofuel is a renewable fuel produced by biological means. Biofuel is very useful because it does not have a finite supply, and it produces fewer ... -
The stereochemical impact of chiral ionic liquids on [2+2] photochemical cycloadditions and aldol reactions
(2020)Eight chiral ionic liquids have been prepared for use as solvents to test whether they can induce enantioselectivity in both photochemical [2+2] cycloadditions and aldol reactions using a variety of starting materials. ... -
The Synthesis and kinetic evaluation of lysosomotropic substrate-based probes for cathepsins B and L
(2015-10-21)Members of the cathepsin family of cysteine proteases are gaining interest as potential imaging biomarkers and drug targets due to their multifunctional roles in a range of diseases such as cancer, asthma and arthritis. ...