Browsing by Committee Member
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A combined method for establishing keratinocyte cultures from cervical biopsy specimens and creating patent-derived 3-dimensional organotypic raft cultures
(2018)High-risk types of human papillomavirus (HPV) are responsible for nearly all instances of cervical cancer, and a significant proportion of head and neck cancers. Studying HPV in the laboratory requires the cultivation of ... -
The effect of polyphenols on the angiotensin II receptor type 1 activation
(2017)Hypertension, an increase in blood pressure, can lead to many serious complications, one of which is heart failure. Angiotensin (Ang) II is associated with hypertension; specifically, the Ang II receptor type 1 (AGTR1) is ... -
Humoral immunity in patients with chronic kidney disease and their response to pneumococcal immunization
(2020)In northwestern Ontario the Indigenous First Nations (FN) population have an increased prevalence of chronic kidney disease (CKD). There is an increased rate of infectious disease caused by Streptococcus pneumoniae ... -
Pull-down of human papillomavirus 16 E6 variants for interactome analysis: a methods development and analysis
(2020)Human Papillomavirus 16 (HPV16) is a double-stranded DNA virus known as a causative agent in almost all cervical cancers and an increasing number of oropharyngeal cancers. Variants of HPV16, such as the Asian-American ... -
Secoisolariciresinol diglucoside reduces cell death and upregulates antioxidants in cardiac iron overload
(2016)Iron is essential to many biological and metabolic processes used in all organisms, but excess iron can result in complications such as cirrhosis, diabetes, and heart failure. Cardiac iron overload has been linked to ...