Browsing by Discipline
Now showing items 1-20 of 112
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Adaptive habitat selection by a single celled alga?
(2014-01-22)Faculty and students in the Department of Biology are bound together by a common interest in explaining the diversity of life, the fit between form and function, and the distribution and abundance of organisms. The research ... -
Algal mixotrophic metabolism for the production of lipids
(2018)The challenges associated with the use of conventional sources of crude oil increase the demand for alternative fuel sources. Biofuels offer the chance of replacing the depleting fossil fuels. However, the food versus ... -
The antioxidant resveratrol down-regulates inflammation in an in vitro model of Pseudomonas aeruginosa infection of lung epithelial cells
(2014-01-22)Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen capable of infecting the lungs and causing severe pulmonary disease in immunocompromised individuals. During the infectious process, P. aeruginosa provokes ... -
Asian-American variant of human papillomavirus 16 E6 promotes the Warburg effect and hypoxia-inducible factor 1 signalling under hypoxia / by Sean Cuninghame.
Infection with high-risk human papillomavirus (HPV) is responsible for nearly all cases of cervical cancer, as well as a significant fraction of other ano-genital and head and neck cancers. Specifically, HPV type 16 (HPV ... -
Aspects of infectious agents and cancer : effects of human Papillomavirus 16 and Escherichia coli on the innate immune defense of human keratinocytes
(2012-11-10)Persistent human papillomavirus (HPV) is the causative agent of cervical cancer and bacterial vaginosis (BV) caused by Escherichia coli (E. coli ) has been implicated as a contributing factor. The innate immune system is ... -
Assessing in vitro DNA repair methods / by Ryan Lehto.
(2010)The DNA molecule is constantly under attack from endogenous and exogenous sources leading to degradation by a variety of forms of damage. In this study current methods of in vitro DNA repair methods were evaluated for ... -
The association between watershed characteristics and mercury concentrations in fish of Northern Ontario lakes
(2014-01-22)Many landscape, limnological, and ecological factors synergistically affect the mercury cycle and subsequently influence total mercury (THg) concentrations in fish. In Chapter 1, the associations between watershed and lake ... -
Bacterial isolation and bioconversion of organic materials to industrial platform chemicals
(2018)Careful selection/isolation of the suitable microbial consortium for enzymatic saccharification of organic matters is a critical step in biofuels production. We isolated strains EF2, OW1-1 and HK2 from intestine of Eisenia ... -
Bioenergetic evaluation of a whole-lake nanosilver addition on Yellow Perch (Perca flavescens)
(2018)Nanosilver (nAg) is an antibacterial and antimicrobial agent. Its wide use in hundreds of commercial products and industrial applications suggests a high potential for release into the environment. Previous research indicates ... -
Biofilm formation of environmental and enterohemorrhagic Escherichia coli / by Stefan Moreira.
(2010)Sample sites : Boulevard Lake & Chippewa Park, Thunder Bay ; Billy Lake, Dorion (Northwestern Ontario). -
Biogenic lead levels in human skeletal remains from the cemetery of the British Royal Navy hospital (1793-1822CE) at English Harbour, Antigua West Indies
(2015)Though lead has been known to be a cause of human poisoning since ancient times, it was a widely used metal. The relationship between ancestry or age and lead exposure in the Colonial period of Antigua, West Indies was ... -
Biological activities of select North American lichens
(2017)The search for novel, pharmacologically significant compounds is a perpetual quest on which biologists, chemists, and bioinformaticians incessantly embark. The sources of these compounds are often of natural origin, making ... -
Black Spruce (Picea mariana) Regeneration in Post-fire Cryptogamic Mats
(2016)Post-fire black spruce (Picea mariana Mill.) regeneration has received considerable attention in management of the boreal forest of eastern Canada. Seedbed quality is a key factor for seed germination and early seedling ... -
Campylobacter jejuni : biofilm formation and oxidative stress
(2009)Campylobacter jejuni (C. jejuni) is a zoonotic pathogen most often associated with poultry and the leading cause of bacterial gastroenteritis in the developed world. It is an obligate microaerobe, requiring low levels of ... -
Cancer biomarker discovery using selected ion flow tube mass spectrometry
(2017)Lung cancer is one of the most common types of neoplasm and is a leading cause of death in Canada. Accurate early diagnosis is key to the effective treatment of the disease, however the current means to do so, such as ... -
The carcinogenic properties of naturally occurring human papillomavirus 16 E6 oncogene variants
(2013-02-03)Human papillomavirus is the causative agent of the 2nd highest occurring cancer in women, cervical cancer, which is the result of expression of the E6 and E7 oncogenes. Here we challenged the dogma that the oncogenic protein ... -
Causes and consequences of population changes in Black Bay Steelhead, Lake Superior
(2019)Understanding species interactions is an important component of fisheries resource management. Like the other Great Lakes, Lake Superior’s fish species composition (and therefore interactions among species) has been changing ... -
Characterization of an arsenite-oxidizing caballeronia sp. soil bacterium and its mutualistic relationship with trifolium pratense for arsenic remediation
(2021)The proposed application of the mutualistic interaction between a native arsenicoxidizing soil bacteria and Trifolium pratense in Northwestern Ontario mine sites is a novel approach to remediation. This thesis studies the ... -
Characterization of rainbow trout (Oncorhynchus mykiss) and fathead minnow (Pimephales promelas) cell lines as models to study pulp and paper effluent effects in fish
(2012-11-10)The effects of aquatic toxicants on fish growth and development have been well-documented, in contrast to the changes in gene expression that necessarily precede them. Many of these toxicants are exogenous compounds that ... -
Characterization of sediment, sewage and 0157 E. coli: a comparison of their virulence genes, biofilm forming capacities, antibiotic resistance and level of reactive oxygen species (ROS)
(2018)Even though sediment Escherichia coli is a common source of contamination in freshwater environments, their virulence and physiological characteristics are not well studied. The goal of this study was to compare the virulence ...
