Browsing by Discipline
Now showing items 1-20 of 41
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Adipose tissue remodeling in response to corticosterone and β3-adrenergic receptor agonist mirabegron
(2022)With the rise of metabolic diseases including obesity and type 2 diabetes, the need to investigate one of the most dynamic endocrine organs is critical for combating these diseases. Adipose tissue (AT) exists predominantly ... -
Bioconversion of crude glycerol to biofuels and value-added bioproducts
(2017)Increasing demand and the rising cost of fossil fuels, as well as a concern for global climate change have shifted global efforts to utilize renewable resources for the production of a ‘greener’ energy replacement. Biodiesel, ... -
Bioremediation of contaminated soils from mine sites using native plants in Northwestern Ontario
(2016)Practical and scientific importance can be found in this research topic since the results directly apply to remediation of industrial and mined lands in the boreal forest region. Plants suitable for phytostabilization of ... -
Carboxyalkylated cullulose nanocrystals for novel applications
(2021)Cellulose nanocrystals (CNC), rigid rod-like nanoparticles, are derived from cellulose through acid hydrolysis and are considered as emerging nanomaterials according to their beneficial properties and commercial availability. ... -
Cardiac oxidative stress and antioxidant status in response to radiation and monocrotaline induced cardiac dysfunction
(2016)Cardiovascular disease is the leading cause of death and disability worldwide. Oxidative stress has been implicated in many types of cardiovascular disease. Chronic cardiac stress conditions have been shown to be associated ... -
Characterization of novel cellulase and glucose isomerase-producing bacteria and optimization of the enzyme production conditions and their potential applications in environment and industry
(2022)Cellulases and glucose isomerases are vital enzymes in converting cellulose into fructose. Cellulases catalyze cellulose conversion to glucose, while glucose isomerase catalyzes the reversible isomerization of glucose ... -
Characterizing the microbial degradation of kraft lignin and lignin-derived compounds
(2014-12-12)Analytical methods for characterizing the microbial degradation of Kraft lignin and lignin-derived compounds were utilized with the goal of biologically generating demethylated lignin for subsequent industrial applications. ... -
Conversion of crude glycerol from the biodiesel industry to value added products
(2017)Crude glycerol is a major by-product of the biodiesel industries. For every 100 kg of biodiesel produced, approximately 10 kg of the byproduct glycerol is generated. With the large increase in biodiesel production, there ... -
Cross-talk of hydrogen sulfide and nitric oxide in vascular endothelial cells
(2014)Gasotransmitters, like hydrogen sulfide (H2S) and nitric oxide (NO), are small gaseous molecules that can be generated in different types of mammalian cells by enzymatic catalyzation. Cystathionine y-lyase (CSE) and ... -
Cystathionine gamma-lyase/hydrogen sulfide system and glucose homeostasis
(2013-02-12)Research in the last twenty years has transformed the role of hydrogen sulfide (H2S) being perceived from a toxic gas to a gaso-transmitter with diverse physiological and pathological significance. Cystathionine gamma-lyase ... -
Design and evaluation of novel fluorescent molecular probes targeting cathepsin B
(2020)Lysosomal cysteine proteinase cathepsin B (CTB) is a member of the cysteine protease family known to participate in intracellular degradation processes and protein turnover in the lysosomes of healthy cells. Cathepsin B ... -
Development of bacterial systems for the production of cellulase and bioethanol
(2013-02-01)The wide varieties of extant bacterial species are often resistant to various environmental stresses. This demonstrates their frequent ability to adapt to and thrive in challenging environments. One such adaptation in ... -
Development of nanostructured material based electrochemical sensors for food safety and quality control
(2019)The issue of foodborne related illnesses due to additives and contaminants poses a significant challenge to food processing industries. Electrochemical-based strategies offer simple and robust analytical tools, which are ... -
The effects of copper, calcium, and nickel on the olfactory response of fathead minnows: from neurophysiology to behaviour
(2014-01-22)The olfactory system is essential for a fish to be successful in an ecological context, and has been demonstrated to be sensitive to a variety of toxicants. The current biotic ligand model (BLM) for copper is an acute-toxicity ... -
Electrokinetic-assisted membrane photobioreactor (EK-MPBR) for municipal wastewater treatment
(2023)Membrane technology and phycoremediation, which utilizes algae for nutrient removal, are two major emerging technologies for wastewater treatment. Membrane photobioreactors (MPBRs) integrate these technologies and provide ... -
Engineering fungi for boosting cellulase production and its potential industrial application
(2013-02-03)Bioconversion of lignocellulosic residues is initiated primarily by microorganisms such as fungi and bacteria which are capable of degrading lignocellulolytic materials. Fungi produce large amounts of extracellular ... -
Environmental Considerations for Wet Mining Peatlands in Northwestern Ontario
(2012-11-10)Signi cant changes in water quality were detected using a Before-After-Control-Impact (BACI) experimental design. Porewater showed increases in pH, alkalinity, conductivity (including Ca, Mg, K, Na), some metals (Sr, Ba, ... -
Exploration of inflammasomes as targets for therapy of Pseudomonas aeruginosa infection
(2018)Pseudomonas aeruginosa is a common Gram-negative opportunistic bacterial pathogen capable of infecting humans with compromised natural defenses and causing severe pulmonary disease. It is the major cause of severe chronic ... -
Functional Imaging of the Lungs using Magnetic Resonance Imaging of Inert Fluorinated Gases
(2016)Fluorine-19 (19F) magnetic resonance imaging (MRI) of the lungs using inhaled inert fluorinated gases can potentially provide high quality anatomical and functional images of the lungs. This technique is able to visualize ... -
H2S as a novel biomarker and therapeutic target for asthma
(2015)Asthma is a chronic inflammatory disease with hyper-responsive bronchoconstriction and airway remodeling, leading to extensive airway narrowing. The pathophysiology of asthma remains unclear. The literature shows that the ...
