Search
Now showing items 1-5 of 5
Physiological adaptations contributing to stress survival in the foodborne pathogen Campylobacter jejuni
(2015-06-15)
n spite of being considered fragile and fastidious, the zoonotic pathogen Campylobacter jejuni remains the leading cause of foodborne bacterial gastroenteritis in the developed world. Lacking many of the stress responses ...
Novel toll-like receptor 4 ligands: synthesis, biological studies and applications in molecular vaccines
(2015-06-15)
Lipid A, a unique disaccharide glycolipid, is the active principle of Gram-negative
bacterial lipopolysaccharide in activating the innate immune response via Toll-like
receptor 4 (TLR4). Given the important role that ...
H2S S-sulfhydration of pyruvate carboxylase in gluconeogenesis and its regulation by Trx1
(2015)
Hydrogen sulfide (H2S), regarded as the third gasotransmitter, plays diverse physiological and pathological roles in the body along with another two gasotransmitters, including nitric oxide (NO) and carbon monoxide (CO). ...
H2S as a novel biomarker and therapeutic target for asthma
(2015)
Asthma is a chronic inflammatory disease with hyper-responsive bronchoconstriction and airway remodeling, leading to extensive airway narrowing. The pathophysiology of asthma remains unclear. The literature shows that the ...
Modelling the molecular mechanisms of biocompatibility of artifical materials
(2015)
One of the most common reasons for implant failure is immune rejection. Implant
rejection leads to additional surgical intervention and, ultimately, increases health
cost as well as recovery time. Within a few hours after ...