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Now showing items 21-23 of 23
Neutrophils in the interface between innate and adaptive immunity in response to Haemophilus influenzae type a
(2022)
Haemophilus influenzae type a (Hia) is a bacterial human pathogen that has emerged as a
significant cause of invasive disease in Canadian Indigenous populations. Protection against
encapsulated bacteria such as Hia is ...
Pre-clinical assessment of the selective androgen receptor modulator RAD140 to increase muscle mass and bone mineral density
(2022)
Selective androgen receptor modulators (SARMs) are important hypertrophic
molecules that pose as potential treatments for many types of myopathy and osteopathy.
The aim of this study was to determine if the SARM RAD140 ...
Evaluation of Anti-E6 Single Domain Antibodies for the Treatment of Human Papillomavirus-related Cancer
(2022)
The HPV16 genome encodes two oncoproteins, E6 and E7, which are essential for viral
carcinogenesis. While E7 promotes cell proliferation, E6 abolishes the resulting p53-dependent
apoptotic response. We hypothesized that ...