Ruthenium-Tris(Pyrazolyl)methane complexes as potential candidates for cancer chemotherapy agents

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Walker, Jesse Morgan

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The MeCN ligands of complex 1 were substitutionally inert, however, under forcing conditions the DMSO ligands of complex 2 were displaced by chelating 1,2-bis(diphenylphosphino)ethane to produce complex 6. Structural characterization of compounds 1-8 was performed by NMR spectroscopy, and an X-ray diffraction analysis of complex 7 provided additional evidence for the proposed structures.

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Antineoplastic agents, Ruthenium compounds, Organoruthenium compounds, organometallic chemistry, Organometallic compounds, Cancer, Chemotherapy, Research

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