Ruthenium-Tris(Pyrazolyl)methane complexes as potential candidates for cancer chemotherapy agents

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dc.contributor.advisorSpivak, Gregory
dc.contributor.advisorGottardo, Christine
dc.contributor.authorWalker, Jesse Morgan
dc.date.accessioned2012-11-11T00:59:51Z
dc.date.available2012-11-11T00:59:51Z
dc.date.created2009
dc.date.issued2009
dc.description.abstractThe MeCN ligands of complex 1 were substitutionally inert, however, under forcing conditions the DMSO ligands of complex 2 were displaced by chelating 1,2-bis(diphenylphosphino)ethane to produce complex 6. Structural characterization of compounds 1-8 was performed by NMR spectroscopy, and an X-ray diffraction analysis of complex 7 provided additional evidence for the proposed structures.en_US
dc.identifier.urihttp://knowledgecommons.lakeheadu.ca/handle/2453/218
dc.language.isoen_USen_US
dc.subjectAntineoplastic agentsen_US
dc.subjectRuthenium compoundsen_US
dc.subjectOrganoruthenium compoundsen_US
dc.subjectorganometallic chemistryen_US
dc.subjectOrganometallic compoundsen_US
dc.subjectCanceren_US
dc.subjectChemotherapyen_US
dc.subjectResearchen_US
dc.titleRuthenium-Tris(Pyrazolyl)methane complexes as potential candidates for cancer chemotherapy agentsen_US
dc.typeThesisen_US
etd.degree.disciplineChemistryen_US
etd.degree.grantorLakehead Universityen_US
etd.degree.levelMasteren_US
etd.degree.nameMaster of Science

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