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Now showing items 728-747 of 3561
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Design and synthesis of small molecule ligands targeting protease-activated receptor 2 as potential diagnostic and therapeutic agents
(2021)Positron emission tomography (PET) imaging requires radionuclides (positron-emitters) labeled molecules (tracers) to image biochemical and physiological processes in vivo and helps diagnose diseases noninvasively. The ... -
Design and testing of a permeable reactive barrier system for treatment of sulphate rich waters at the former steep rock iron mine, Atikokan, Ontario
(2015)Acid mine drainage (AMD) is one of the greatest challenges facing the mining industry globally. Methods for addressing this issue have been widely studied; however, few studies have addressed sites with a less common water ... -
Design methodology for Class D ultrasound transducer drivers
(2021)Ultrasound refers to sound waves with frequencies above the upper limit of human hearing. Due to the high frequency, the energy can be concentrated and used for therapeutic applications, such as ultrasound imaging ... -
A Design Methodology for Low Power CMOS Current Source
(2016)A current reference circuit is a basic building block in analog, digital and mixed-signal design systems. This work focuses on one type of integrated CMOS current reference circuit. This source only uses one type of ... -
Design of a 6-DOF haptic interface for robotic teleoperation
(2008)Teleoperation has become increasingly important in medical applications, handling hazardous materials, as well as in other robotics applications. Force feedback in such systems is essential; therefore a haptic device is ... -
Design of a beam-steerable microstrip line based leaky wave antenna using uniaxial field programmable microwave substrate (FPMS)
(2021)The ever-growing wireless technologies of today are pushing the limits of the state-of-the-art radio frequency (RF) components design. One special requirement which is widely needed in modern applications is for the RF ... -
Design of a polarization reconfigurable and frequency tunable patch antenna system on a magnetic substrate
(2024)Modern radio frequency (RF) and microwave components are continuously evolving to meet the demands of new wireless technologies. One such demand is the ability of these components to be agile and smart. Thus, the rationale ... -
Design of polarization reconfigurable beam-steerable and frequency tunable FPMS based SIW-slot antennas
(2022)With the rapid evolution of modern and smart communication technologies such as 5th generation of mobile network (5G), (internet of things) IoT, Autonomous Vehicles, Aviation Technology, etc., the need for reconfigurable ... -
The design of Zr metal-organic frameworks in the detection and neutralization of organophosphorus based nerve agents and pesticides
(2022)Organophosphates are ubiquitous in uses ranging from chemical warfare agents (CWA’s) to detergents. In between these two extreme uses lie organophosphorus-based agrichemicals, primarily pesticides, which are applied in ... -
Design, analysis and passive balance control of a 7-DOF biped robot
(2007)Biped robots have many advantages than traditional wheeled or tracked robots. They have better mobility in rough terrain and can travel on discontinuous path. The legs can also provide an active suspension that decouples ... -
Design, development and usability evaluation of social system interface and development of computational model
(2021)In recent times, methods of computational intelligence (CI) that aim to solve real-life problems are developed by computer science researchers in collaboration with domain experts. There has also been an increased emphasis ... -
Design, simulation and control of a 12 DOF biped robot
(2012-11-10)The field of humanoid robotics has in the last several decades taken off as an active area of research. The goal of this field id to build robots which by having a human-like form will be able to work in environments ... -
The design, synthesis and enzymatic evaluation of aminocyclitol inhibitors of glucocerebrosidase
(2014-01-22)Gaucher disease, the most common lysosomal storage disorder, is caused by mutations in the GBA gene which codes for the enzyme glucocerebrosidase (GCase) resulting in its deficiency. GCase deficiency results in the ... -
Design, synthesis, and evaluation of novel lysophosphatidic acid receptor-targeting small molecules as therapeutic and diagnostic agents
(2023)Breast cancer has the highest incidence rate of all cancers among Canadian women and accounts for nearly 14% of all cancer-related deaths in Canada. This type of cancer is often detected using medical imaging modalities ... -
Designing a secure ubiquitous mammography consultation system
(2004)This thesis attempts to design and develop a prototype for mammography image consultation that can work securely within a ubiquitous environment. Mammogram images differ largely from other type of images and it requires ... -
Detecting Crohn’s disease from high resolution endoscopy videos: the thick data approach
(2023)Detecting diseases in high resolution endoscopy videos can be done in several ways depending on the methodology for detection. One such method that has been a hot topic in the field of medical technology research is the ... -
Detecting depression and malingering using response times on the Personality Assessment Inventory
(2000)The detection of individuals who are malingering psychological dysfunction has proven to be a difficult task (Rogers, 1997). This study was conducted to investigate whether response times on the Personality Assessment ... -
Detecting trends in walleye (Stizostedion v. vitreum, Mitchill) abundance using catch-effort data
(1995)Three methods of analyzing catch-effort data were investigated regarding their relationship to walleye abundance: mean CUE, Gini coefficient and the relative frequency of zero CUE (RFZ). Walleye recreational fishery ... -
Detection and assessment of Armillaria in young conifer plantations of northwestern Ontario and northeastern China
(1991)Methods for detecting and evaluating Armillaria in plantations were compared in a series of studies. The purposes of the studies were to standardize the Armillaria trapping technique, and to determine if it could be used ... -
Detection and characterization of DNA damage
(2009)The DNA molecule is constantly subjected to endogenous and exogenous sources of damage which if left unrepaired can lead to genotoxic and cytotoxic outcomes. These lesions have been implicated in the development of numerous ...